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EAST COAST CHAPTER OF DAHSHU

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RUI (SAMMI) TANG

CHAIR

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Dr. Rui (Sammi) Tang is a leading expert of biostatistics/bioinformatics in the biotech/pharmaceutical industry and she is currently the Senior Director, Head of Biostatistics Department leading the Biostats and Programming team at Servier Pharmaceuticals US. Prior to join Servier she was the Therapeutic Area head of Oncology, Transplants, Ophthalmology and prematurity neonates programs at Shire pharmaceutical. Prior to that she was at Vertex pharmaceutical leading Oncology and Hematology pipelines. Before that she also has worked at Amgen for about 8 years, Mayo clinical biostatistics and Merck shortly. Previously she served as the biostatistics lead of Companion Diagnostics and the Global Statistics Lead for multiple oncology clinical programs from early phase to late phase at Amgen. Sammi has great experience in CDRH, CBER, CDER, health Canada, EMA and Asian regulatory agencies interactions. Sammi’s research interests are primarily in the area of adaptive clinical trial design and biomarker subgroup related statistical issues in precision medicine. She has authored more than 30 articles in peer-reviewed scientific journals on methodology, study design, data analysis and reporting and is a co-inventor of several patents. Besides her daily work, she actively promotes data science through many of her volunteer activities: Sammi is co-founder of DahShu which is a 501(c)(3) non-profit organization, founded to promote research and education in data sciences with almost 2000 members internationally. She serves in the SCT (Society of Clinical Trials) scientific program committee and development committee since 2013 to help organize the annual international conference. She is leading teams in the DIA (Drug Information Association) Adaptive design working group of oncology drug development and small population working group for rare disease statistical methodology development. She is also an active member in ASA (American Statistics Association) and ICSA (International Chinese Statistics Association) to serve the biostatistics and data science professional community.

Sammi graduated from the University of Michigan Technology University with a PhD in statistics Genetics.
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CHANGYU SHEN

VP OF SCIENTIFIC OUTREACH

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Changyu Shen is an Associate Professor at Harvard Medical School and the Statistical Director of the Smith Center for Outcomes Research in Cardiology at Beth Israel Deaconess Medical Center. He received his PhD in Biostatistics from University of Pittsburgh. Dr. Shen has a broad spectrum of research experience in statistical methodology development including missing data, causal inference, heterogeneity of treatment effect, randomized clinical trials and OMICs. He also has extensive experience in collaborative clinical research with a focus in cardiovascular diseases. Currently, Dr. Shen’s research is focused on statistical development and applications in general clinical research, healthcare policy and regulatory science.
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JOSEPH C. CAPPELLERI

VP OF HEALTHCARE INDUSTRIAL LIAISON

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Joseph C. Cappelleri earned his MS in statistics from the City University of New York, PhD in psychometrics from Cornell University, and MPH in epidemiology from Harvard University. Dr. Cappelleri is an executive director of biostatistics at Pfizer Inc and president-elect of the New England Statistical Society. He has co-authored and presented extensively on clinical and methodological topics, including on regression-discontinuity designs, meta-analysis, and health measurement scales. He is a Fellow of the American Statistical Association.

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KUN CHEN

VP OF ACADEMIC LIAISON

Dr. Kun Chen is an Associate Professor in the Department of Statistics, University of Connecticut (UConn), and a Research Fellow at the Center for Population Health, UConn Health Center. Chen’s research mainly focuses on multivariate statistical learning, high-dimensional statistics, and healthcare analytics with large-scale heterogeneous data. He has extensive interdisciplinary research experience in a variety of fields including insurance, ecology, biology, agriculture, medical imaging, and public health. Chen's research projects have received funding from the National Institutes of Health (NIH), the Simons Foundation, and the National Science Foundation (NSF). He has received Recognition for Teaching Excellence at UConn for multiple times. Chen is an elected member of the International Statistical Institute, and a member of American Statistical Association and International Chinese Statistical Association. Chen servers as Secretary of the New England Statistical Society since its establishment in 2017.


Chen received his B.Econ. in Finance and Dual B.S. in Computer Science & Technology from the University of Science and Technology of China in 2003, his M.S. in Statistics from the University of Alaska Fairbanks in 2007, and his PhD in Statistics from the University of Iowa in 2011. Before joining UConn, he was on the faculty of Kansas State University from 2011 to 2013.
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JIARUI ZHANG

STUDENT VOLUNTEER LEADER

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Jiarui Zhang is currently an Informatics Scientist in Agios Pharmaceuticals and his work focuses on leveraging high-throughput data to impact cancer drug discovery and cancer precision medicine. He achieved his PhD in Molecular & Translational Medicine from Boston University School of Medicine, where he leveraged computational approaches to develop genomic biomarkers for lung cancer early interception. Before coming to the US, he received his medical degree from Fudan University in Shanghai, China, where he practiced medicine and conducted immuno-oncology and cancer epidemiology research. He is dedicated to investigating and translating novel omics findings to impact precision care for cancer patients.

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